Successful treatment of xanthoma disseminatum with pulsed dye laser: A case report

• Published in: Australasian journal of dermatology Vol. 65; no. 3; pp. e37 - e40
• Main Authors: Jung, Jin Woong, Kim, Joon‐Goon, Alwabel, Albaraa Abdullatif A., Jung, Yeon Woo, Chung, Kee‐Yang
• Format: Journal Article
• Language: English
• Published: Australia Wiley Subscription Services, Inc 01.05.2024
• Subjects: Accidents, Traffic; Adult; Brain Injuries, Traumatic - complications; Burns - complications; Dyes; Facial Dermatoses - pathology; Facial Dermatoses - radiotherapy; Facial Injuries - complications; Histiocytosis; Histiocytosis, Non-Langerhans-Cell - pathology; Histiocytosis, Non-Langerhans-Cell - surgery; Humans; Lasers; Lasers, Dye - therapeutic use; Low-Level Light Therapy - methods; Male; pulsed dye laser; Skin diseases; Skin lesions; traffic accident; Traumatic brain injury; Xanthoma; xanthoma disseminatum; traffic accident; xanthoma disseminatum; pulsed dye laser
• ISSN: 0004-8380; 1440-0960; 1440-0960
• DOI: 10.1111/ajd.14209

Xanthoma disseminatum is a rare form of non‐Langerhans cell histiocytosis with limited treatment options due to its unknown aetiology and diffuse skin lesions. This case report presents the successful treatment of a 31‐year‐old male with severe pan‐facial xanthoma disseminatum lesions following a facial burn and traumatic brain injury resulting from a car accident. After 5 sessions of monthly pulsed dye laser treatment, there was a clinically significant reduction in the lesions. Over the course of 3 years, the patient underwent a series of monthly pulsed dye laser treatments, and the lesions were almost cleared. These findings suggest that pulsed dye laser therapy may offer an effective treatment option for managing xanthoma disseminatum. This is the first report on use of the pulsed dye laser for treatment of xanthoma disseminatum.