Pleomorphic rhabdomyosarcoma presenting as a hypopharyngeal mass

Background Rhabdomyosarcoma (RMS) is a rare malignancy derived from skeletal muscle with approximately 40% of cases involving the head and neck. The pleomorphic variant, however, most commonly occurs in the extremities and has never, to our knowledge, been described in the pharynx. Methods A 46‐year...

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Published inHead & neck Vol. 37; no. 7; pp. E85 - E87
Main Authors Crane, Ryan A., Johnson, Christopher M., Grice, Guerard P., Mullin, David P., Bach, Kevin K., Eisele, David W.
Format Journal Article
LanguageEnglish
Published United States Wiley Subscription Services, Inc 01.07.2015
Subjects
Diagnosis, Differential
head and neck cancer
Hemoptysis
Humans
Hypopharyngeal Neoplasms - diagnosis
hypopharynx
Hypopharynx - pathology
Laryngoscopes
Male
malignancy
Middle Aged
rhabdomyosarcoma
Rhabdomyosarcoma - diagnosis
staging
Tomography, X-Ray Computed
hypopharynx
head and neck cancer
malignancy
rhabdomyosarcoma
staging
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Summary:Background Rhabdomyosarcoma (RMS) is a rare malignancy derived from skeletal muscle with approximately 40% of cases involving the head and neck. The pleomorphic variant, however, most commonly occurs in the extremities and has never, to our knowledge, been described in the pharynx. Methods A 46‐year‐old man with no significant medical history presented to the emergency department complaining of hemoptysis. A CT scan of the head and neck revealed a hypopharyngeal mass originally favored to be a benign process. Results Operative endoscopy revealed a previously unseen mucosal ulceration, and subsequent biopsy resulted in the final diagnosis of pleomorphic RMS. Conclusion Although quite rare, RMS should be considered in the differential diagnosis of a hypopharyngeal mass. This articleis a U.S. Government work and is in the public domain in the USA. Head Neck 37: E85–E87, 2015
Bibliography:Ryan A. Crane, Christopher M. Johnson, and David P. Mullin are military service members. This work was prepared as part of our official duties. Title 17, USC, § 105 provides that “Copyright protection under this title is not available for any work of the United States Government.” Title 17, USC, § 101 defines a U.S. Government work as a work prepared by a military service member or employee of the U.S. Government as part of that person's official duties.
The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the Navy, Department of Defense, or the United States Government.
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ISSN:1043-3074
1097-0347
DOI:10.1002/hed.23876