Formulation of an Early Warning Infectivity Score System for Adult Patients with Acute Bacterial Diarrhea

• Published in: Biomedical and environmental sciences Vol. 27; no. 1; pp. 65 - 69
• Main Authors: WANG, Yan, ZHANG, Tian Peng, XIAO, Hong Li, QI, Hai Yu, YIN, Cheng Hong
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 2014; Department of Emergency, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China%Department of Infectious Disease and Critical Care Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
• Subjects: Abdominal Pain - diagnosis; Acute Disease; Adult; Bacterial Infections - classification; Bacterial Infections - diagnosis; Bacterial Infections - microbiology; Body Temperature; China - epidemiology; Diarrhea - diagnosis; Diarrhea - microbiology; Feces - cytology; Female; Humans; Leukocytes - cytology; Logistic Models; Logistic回归; logistic回归分析; Male; Middle Aged; Risk Factors; Young Adult; 急性腹泻; 感染性; 细菌性腹泻; 评分系统; 配方; 预警; China
• ISSN: 0895-3988; 2214-0190
• DOI: 10.3967/bes2014.018

The aim of our study was to develop a scoring system to predict whether diarrhea is of a bacterial origin and whether the diarrheal patients constitute a potential source of infection to others. Adults with acute diarrhea （n=424） were enrolled in the study. Logistic regression and standard regression coefficients were used to formulate the Early Warning Infectivity Score System for Adults with Acute Bacterial Diarrhea （EWIS-ABD）. Four risk factors were identified by logistic regression, including body temperature （P〈0.01）, abdominal pain （P〈0.01）, leukocyte count in stool （P〈0.01）, and unclean dietary history （P〈0.01）. EWIS-ABD was thus developed, in which the value 〉5 points was set as an indicator of bacterial diarrhea. The incidence of bacterial diarrhea increased along with the elevated score. EWIS-ABD was more specific for bacterial diarrhea than for viral diarrhea. The accuracy and reliability of EWIS-ABD was high by prospective validation in 478 patients with acute diarrhea.