Facile synthesis of α-fluoro substituted amidines from imidoyl chlorides and some of its application

A series of α-fluoro subustituted amidines were synthesized from corresponding fluorinated imidoyl chlorides in good to excellent yields and some of its applications are outlined in our programs.

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Bibliographic Details
Published inJournal of fluorine chemistry Vol. 127; no. 9; pp. 1168 - 1174
Main Authors Wu, Yong-Ming, Zhang, Min, Li, Yi-Qun
Format Journal Article
LanguageEnglish
Published LAUSANNE Elsevier B.V 01.09.2006
Elsevier
Subjects
1,4-Dihydropyridine
Aryl amination
Chemistry
Chemistry, Inorganic & Nuclear
Chemistry, Organic
Fluorinated aminals
Fluorinated benzoimidazole
Physical Sciences
Science & Technology
α-Fluoro subustituted amidines
α-Fluoro subustituted imidoyl chlorides
α-Fluoro subustituted amidines
Aryl amination
Fluorinated aminals
Fluorinated benzoimidazole
1,4-Dihydropyridine
α-Fluoro subustituted imidoyl chlorides
alpha-fluoro subustituted amidines
alpha-fluoro subustituted imidoyl chlorides
DESIGN
fluorinated benzoimidazole
aryl amination
INHIBITORS
fluorinated aminals
ANTAGONISTS
1,4-dihydropyridine
DERIVATIVES
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Summary:A series of α-fluoro subustituted amidines were synthesized from corresponding fluorinated imidoyl chlorides in good to excellent yields and some of its applications are outlined in our programs.
ISSN:0022-1139
1873-3328
DOI:10.1016/j.jfluchem.2006.06.008