UHPLC-Orbitrap screening of oleraindoles in hydromethanolic extracts of Portulaca oleracea

Purslane ( Portulaca oleracea L., Portulacaceae) is a widespread edible plant with significant ethnobotanical and ethnopharmacological importance. The plant is characteristic for the presence of a class of indoline amide glucoside alkaloids, called cyclo-dopa amides, or oleraceins. Additionally, a n...

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Published inFarmacija Vol. 70; no. 4; pp. 1521 - 1527
Main Authors Voynikov, Yulian, Gevrenova, Reneta, Zheleva-Dimitrova, Dimitrina, Balabanova, Vessela, Nikolova, Irina, Marinov, Lyubomir, Benbassat, Iossif, Momekov, Georgi
Format Journal Article
LanguageEnglish
Published Pensoft Publishers 18.12.2023
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Summary:Purslane ( Portulaca oleracea L., Portulacaceae) is a widespread edible plant with significant ethnobotanical and ethnopharmacological importance. The plant is characteristic for the presence of a class of indoline amide glucoside alkaloids, called cyclo-dopa amides, or oleraceins. Additionally, a new, structurally similar to oleraceins, class of indole amides have been discovered recently, called oleraindoles. These compounds have been evaluated to possess antiinflammatory and anticholinesterase activities. Herein, utilizing UHPLC-Orbitrap-MS with MS 2 filtering by diagnostic ion filtering (DIF), and diagnostic difference filtering (DDF) using different data analysis tools, eight compounds with oleraindole structure were tentatively identified.
ISSN:0428-0296
2603-557X
DOI:10.3897/pharmacia.70.e113577