Proposed shorter duration protocols for measuring resting energy expenditure utilizing whole-room indirect calorimetry

• Published in: International Journal of Obesity Vol. 49; no. 4; pp. 731 - 736
• Main Authors: Rising, Russell, Kittrell, Hannah D., Albu, Jeanine B.
• Format: Journal Article
• Language: English
• Published: England Nature Publishing Group 01.04.2025; Nature Publishing Group UK
• Subjects: Adult; Basal Metabolism - physiology; Calorimetry; Calorimetry, Indirect - methods; Carbon dioxide; Carbon Dioxide - metabolism; Combustion; Consumption; Energy expenditure; Energy Metabolism - physiology; Extrapolation; Female; Heat measurement; Humans; Linearity; Male; Metabolism; Oxygen Consumption - physiology; Propane; Respiratory quotient; Stoichiometry; Time Factors; Vanadium oxides; Weight loss
• ISSN: 0307-0565; 1476-5497; 1476-5497
• DOI: 10.1038/s41366-024-01667-4

Sixty minutes is currently the shortest testing duration for 24-h resting energy expenditure (24-h REE) utilizing whole-room indirect calorimetry. Show that recalculated 30-min extrapolated 24-h REE from previously published 60-min metabolic data are valid. Propane consumption linearity was determined through an 8-h combustion test. Thereafter, metabolic data for 24-h extrapolated ventilation rates of oxygen (VO ; l/d), carbon dioxide (VCO ; l/d), respiratory quotient (RQ; VCO /VO ), and REE (MJ/d) from ten 60-min propane combustion tests were recalculated to reflect a 30-min testing duration. A similar analysis was performed utilizing data from 60-min subject metabolic measurements within a whole-room indirect calorimeter (4597 liters) specific for measuring resting energy expenditure (REE). Statistical (p < 0.05) comparisons between recalculated and original 60-min metabolic data were determined by SPSS (version 29). Propane consumption during a combustion test was found to be linear for up to 8-h. Furthermore, no differences existed between propane stoichiometry and combustion for any of the extrapolated 24-h metabolic parameters when recalculated from 60-min propane combustion data to reflect a 30-min duration. Finally, similar results were obtained for all recalculated subject metabolic data. Recalculated extrapolated 24-h metabolic data derived from a 30-min testing duration appear to be valid. This suggests that whole-room indirect calorimetry could be an adjunct for various weight loss or other programs where accurate metabolic measurements are required.