Polyvinylpyrrolidone-stabilized magnetic nickel nanochains for cancer hyperthermia and catalysis applications

• Published in: RSC advances Vol. 5; no. 29; pp. 22965 - 22971
• Main Authors: Wu, Jian, Zhou, Wei, Cheng, Qingmei, Yang, Jinglei
• Format: Journal Article
• Language: English
• Published: 01.01.2015
• Subjects: Cancer; Catalysis; Catalysts; Effectiveness; Hyperthermia; Nanostructure; Nickel; Performance enhancement
• ISSN: 2046-2069; 2046-2069
• DOI: 10.1039/c4ra10545a

In this study, we report a novel polyvinylpyrrolidone-stabilized magnetic nickel nanochain (Ni-NC@PVP) using a simple solvothermal method for potential cancer hyperthermia and catalytic applications. The water-soluble Ni-NC@PVP exhibits excellent magnetic hyperthermia properties and low toxicity. In order to investigate the apoptotic hyperthermia efficacy of Ni-NC@PVP in skin cancer cells, we also explore the interaction of Ni-NC@PVP with cancer cells, which exhibits excellent antitumor efficacy on B16 cells. In addition, as a magnetically separable catalyst, it also shows excellent catalytic activity and durability for the selective hydrogenation of acetophenone to 1-phenylethanol. The enhanced performance demonstrates the possibility for designing new multifunctional nanomaterial with improved performances for biomedical therapies and green catalysis. Novel polyvinylpyrrolidone-stabilized magnetic nickel nanochain (Ni-NC@PVP) have been reported by simple solvothermal method for potential cancer hyperthermia and catalytic applications.