influence of the limk1 gene polymorphism on learning acquisition and memory formation, pCREB distribution and aggregate formation in neuromuscular junctions in Drosophila melanogaster

• Published in: Russian journal of genetics Vol. 51; no. 6; pp. 582 - 590
• Main Authors: Kaminskaya, A. N, Nikitina, E. A, Medvedeva, A. V, Gerasimenko, M. S, Chernikova, D. A, Savvateeva-Popova, E. V
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01.06.2015
• Subjects: adults; Animal Genetics and Genomics; Biomedical and Life Sciences; Biomedicine; courtship; Drosophila melanogaster; General Genetics; genes; genetic polymorphism; Human Genetics; imagos; memory; Microbial Genetics and Genomics; mutants; nerve tissue; synapse; Courtship Behavior; Sound Production; Dorsal Nerve; Neuromuscular Junction; Beta Amyloid Precursor Protein

We have shown previously that the polymorphic structure of the limk1 gene in Drosophila leads to changes in LIMK1 content and to defects in courtship behavior, sound production, and learning/memory. The results of the present study of three wild-type strains and mutant agn ᵗˢ³ with altered limk1 str...