Organo-nanocatalysis: An emergent green methodology for construction of bioactive oxazines and thiazines under ultrasonic irradiation

A synergistic catalysts system ZnO NPs and Malic acid was used for the highly efficient and eco-friendly synthesis of oxazines and thiazines derivatives. Aldehyde, urea and alkyne derivatives are used as reactants under ultrasonication, which not only allows clean and rapid alteration but also simpl...

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Bibliographic Details
Published inJournal of molecular structure Vol. 1196; pp. 54 - 57
Main Authors Ansari, Mohd Danish, Sagir, Hozeyfa, Yadav, Vijay B., Yadav, Neetu, Verma, Ankit, Siddiqui, I.R.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 15.11.2019
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Summary:A synergistic catalysts system ZnO NPs and Malic acid was used for the highly efficient and eco-friendly synthesis of oxazines and thiazines derivatives. Aldehyde, urea and alkyne derivatives are used as reactants under ultrasonication, which not only allows clean and rapid alteration but also simplifies experimental setup. High yields, environmentally benigness, simple work-up and shorter reaction times are some remarkable advantages of this strategy. [Display omitted] •Synthesis of oxazines and thiazines was established with the help of synergistic catalysts system under ultrasonication.•Combination of ZnO NPs and Malic acid worked as a green and recyclable promoter of this reaction.•Ultrasonic irradiation provide a clean and rapid alteration.•High yields, environmentally benign and shorter reaction times are some additional advantages of this strategy.
ISSN:0022-2860
1872-8014
DOI:10.1016/j.molstruc.2019.06.052