Using Clinical Scenarios to Understand Preventability of Clostridium difficile Infections by Inpatient Antibiotic Stewardship Programs

CO CDI cases made up 28% of all CDIs detected during the study period. Because other studies found that approximately 50% of hospitalized CDI cases are CO,6 an even greater proportion of CDI cases at other hospitals may not be prevented by activities of their local inpatient ASPs. While inpatient AS...

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Published inInfection control and hospital epidemiology Vol. 38; no. 6; pp. 747 - 749
Main Authors Seidelman, Jessica, Dicks, Kristen V, Durkin, Michael J, Baker, Arthur W, Moehring, Rebekah W, Anderson, Deverick J, Sexton, Daniel J, Chen, Luke F, Lewis, Sarah S
Format Journal Article
LanguageEnglish
Published United States Cambridge University Press 01.06.2017
Subjects
Anti-Bacterial Agents - therapeutic use
Antibiotics
Antimicrobial Stewardship
Clostridioides difficile - drug effects
Clostridium Infections - drug therapy
Clostridium Infections - epidemiology
Clostridium Infections - prevention & control
Cohort analysis
Delphi Technique
Hospitals
Humans
Infections
Infectious diseases
Inpatients
North Carolina - epidemiology
Nursing
Ostomy
Patients
Polls & surveys
Retrospective Studies
Tertiary Care Centers
North Carolina
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Summary:CO CDI cases made up 28% of all CDIs detected during the study period. Because other studies found that approximately 50% of hospitalized CDI cases are CO,6 an even greater proportion of CDI cases at other hospitals may not be prevented by activities of their local inpatient ASPs. While inpatient ASPs may not be able to affect the development of CO CDI, interventions implemented by outpatient ASPs could have a big impact because most antibiotics are prescribed in the outpatient setting, where overuse is common. [...]2 prior systematic reviews have concluded that outpatient ASPs can reduce inappropriate use and/or selection of antibiotics.7,8 Indeed, the Centers for Medicare and Medicaid Services (CMS) has commenced discussions on policies relating to ASP interventions in ambulatory clinics and in long-term-care facilities outside acute-care hospitals.9 Our data support the need for more comprehensive outpatient ASP interventions. [...]there was a low response rate in round 2 of the survey.
Bibliography:ObjectType-Article-1
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ISSN:0899-823X
1559-6834
DOI:10.1017/ice.2017.32