Novel highly selective and sensitive fluorescent sensor for copper detection based on N-acylhydrazone acridone derivative

• Published in: Journal of molecular structure Vol. 1199; p. 126990
• Main Authors: Aarjane, Mohammed, Slassi, Siham, Amine, Amina
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 05.01.2020
• Subjects: Acridone; Acylhydrazone; Copper ion; Fluorescent chemosensor; Quenching; Copper ion; Fluorescent chemosensor; Acylhydrazone; Acridone; Quenching
• ISSN: 0022-2860; 1872-8014
• DOI: 10.1016/j.molstruc.2019.126990

A new N-acylhydrazone based on acridone (S1) was synthesized by Schiff base condensation of 2-(9-oxoacridin-10-yl)acetohydrazide and salicylaldehyde and studied as selective fluorescence turn-off sensing towards Cu2+ ions in aqueous media. S1 demonstrated fluorescence turn-off sensing towards Cu2+ ions. Conversely, the metal ions K+, Mg2+, Zn2+, Fe2+, Al3+, Pb2+, Cr2+, Cd2+, Ag+, Fe3+, Ba2+, Hg2+, Mn2+, Co2+, and Ni2+ produced only minor decrease in the fluorescence of the system. The binding ratio of S1–Cu2+ complex was determined from the Job plot to be 1:2. Moreover, the S1–Cu2+ complex showed good fluorescence turn-off in presence of different counter ions of copper. In addition, the detection limit of S1 towards Cu2+ ions is 0.80 μM, which is enough for sensing the Cu2+ in the biological system and water within the U.S Environmental Protection Agency limit (∼20 μM). [Display omitted] •A new chemosensor S1 was facilely synthesized by Schiff base condensation from acridone.•S1 showed highly selective fluorescence turn-off sensing towards Cu2+ in aqueous media.•The detection limit sensing for Cu2+ in aqueous media was estimated to be 0.80 μM.