Successful treatment of gastric adenocarcinoma in a Meckel's diverticulum with pemetrexed plus carboplatin

• Published in: Japanese journal of clinical oncology Vol. 40; no. 11; pp. 1110 - 1112
• Main Authors: Muto, Osamu, Munakata, Masaki, Iino, Chikara, Sakata, Yuh
• Format: Journal Article
• Language: English
• Published: England 01.11.2010
• Subjects: Adenocarcinoma - drug therapy; Adenocarcinoma - pathology; Adult; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Carboplatin - administration & dosage; Gastric Mucosa - pathology; Glutamates - administration & dosage; Guanine - administration & dosage; Guanine - analogs & derivatives; Humans; Male; Meckel Diverticulum - drug therapy; Meckel Diverticulum - pathology; Neoplasm Recurrence, Local - diagnosis; Neoplasm Recurrence, Local - drug therapy; Neoplasm Recurrence, Local - pathology; Pemetrexed; Stomach Neoplasms - drug therapy; Stomach Neoplasms - pathology; Tomography, X-Ray Computed; Treatment Outcome
• ISSN: 0368-2811; 1465-3621
• DOI: 10.1093/jjco/hyq092

A 42-year-old man was found to have an adenocarcinoma arising from ectopic gastric mucosa in Meckel's diverticulum, as diagnosed with surgical pathology. Recurrence was recognized with massive ascites at 1 year and 6 months after surgery. Chemotherapy in the first and second lines was not effective. In the third line of chemotherapy, pemetrexed and carboplatin were both administered and this resulted in a good response for massive ascites. This palliative therapy was effective and safe.