COMPARATIVE STUDY OF THE EFFECTS OF LOW-LEVEL LASER AND LOW-INTENSITY ULTRASOUND ASSOCIATED WITH BIOSILICATE® ON THE PROCESS OF BONE REPAIR IN THE RAT TIBIA

Objective: Verify the effects of the association between Biosilicate® and ultrasound and, Biosilicate® and laser in bone consolidation process of rats, through the biomechanical and histological analysis. Methods: Forthy male rats were used. The animals were randomized into four groups (n=10): contr...

Full description

Saved in:
Bibliographic Details
Published inRevista brasileira de ortopedia (English ed.) Vol. 47; no. 1; pp. 102 - 107
Main Authors Oliveira, Poliani de, Fernandes, Kelly Rosseti, Sperandio, Evandro Fornias, Pastor, Fabio Alexandre Casarin, Nonaka, Keico Okino, Parizotto, Nivaldo Antonio, Renno, Ana Claudia Muniz
Format Journal Article
LanguageEnglish
Published Brazil Elsevier Editora Ltda 01.01.2012
Elsevier
Subjects
Biocompatible Materials
Bone Tissue
Laser
Original
Rats
ultrasound
Rats
Bone Tissue
Biocompatible Materials
ultrasound
Laser
Online AccessGet full text

Cover

More Information
Summary:Objective: Verify the effects of the association between Biosilicate® and ultrasound and, Biosilicate® and laser in bone consolidation process of rats, through the biomechanical and histological analysis. Methods: Forthy male rats were used. The animals were randomized into four groups (n=10): control group fracture no treated (CGF); group treated with Biosilicate® (BG); group treated with Biosilicate® and laser (BLG); group treated with Biosilicate® and ultrasound (BUG). Results: The biomechanical analysis showed no significant difference among any groups after 14 days post-surgery. In the morphometric analysis, the control group showed moderate presence of new formed bone tissue inside the defects areas and the Biosilicate® group showed similar results. Despite those facts, the biomaterial osteogenic potential was demonstrated by the great amount of cells and bone tissue around the particles. Curiously, the Biosilicate® plus laser or ultrasound groups showed lower amounts of bone tissue deposition when compared with control fracture and Biosilicate® groups. Conclusion: The data from this study can conclude that Biosilicate® was able to accelerate and optimized the bone consolidation, through the modulation of the inflammatory process and the stimulation of new bone formation. However, when resources were associated, there are no positive results.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2255-4971
2255-4971
DOI:10.1016/S2255-4971(15)30352-9