Genotypic classification of childhood acute lymphoid leukemia

Appropriate classification of disease is essential not only to the study of its causation and pathophysiology but to selection of appropriate treatment. The development of morphologic and immunologic methods to classify leukemia have been largely driven by the need to select treatment as effective a...

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Bibliographic Details
Published inLeukemia Vol. 13 Suppl 1; pp. S90 - S91
Main Author Pinkel, D
Format Journal Article
LanguageEnglish
Published England Nature Publishing Group 01.04.1999
Subjects
Acute lymphoblastic leukemia
Aneuploidy
Biomarkers, Tumor - genetics
Child, Preschool
Children
Disease-Free Survival
Genotype
Humans
Infant
Infant, Newborn
Leukemia
Lymphatic leukemia
Oncogene Proteins, Fusion - genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma - classification
Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality
Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology
Prognosis
Receptors, Antigen, T-Cell - genetics
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Summary:Appropriate classification of disease is essential not only to the study of its causation and pathophysiology but to selection of appropriate treatment. The development of morphologic and immunologic methods to classify leukemia have been largely driven by the need to select treatment as effective agents have become available since Lissauer's success with arsenic in myeloid leukemia and Farber et al's with antifolates in lymphoid leukemia.
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ISSN:0887-6924
1476-5551
DOI:10.1038/sj.leu.2401317