Oat beta glucans anti-inflammatory actions in leg exercise stress

• Published in: Nutrition and food science Vol. 51; no. 1; pp. 1 - 9
• Main Authors: Thompson, Jennifer Creamer, Kirby, Timothy, DiSilvestro, Robert A
• Format: Journal Article
• Language: English
• Published: Bradford Emerald Publishing Limited 25.01.2021; Emerald Group Publishing Limited
• Subjects: Dietary fiber; Digestive system; Glucan; Glucans; Inflammation; Ingestion; Intervention; Metabolism; Muscles; Musculoskeletal system; Peroxidase; Placebos; Pretreatment; Skeletal muscle; Statistical analysis; Stress; Weightlifting; Young adults; β-Glucan; United States > US; Ohio; Myeloperoxidase; Inflammation; Exercise; Glucans; Fiber
• ISSN: 0034-6659; 1758-6917
• DOI: 10.1108/NFS-01-2020-0011

Purpose Dietary fiber is not traditionally considered to have anti-inflammatory actions in skeletal muscle. This study aims to test the hypothesis that oat β-glucans fiber intake can inhibit exercise-induced inflammation. Design/methodology/approach Young adult males (age 18-30 years) consumed either oat bran β-glucans (2 × 1.5 g fiber/day) or placebo for 4 weeks (Trial 1: N = 11 for placebo, N = 9 for glucan; Trial 2: N = 7 for placebo, N = 8 for glucan). Muscle inflammatory stress was induced at baseline and post-intervention using a leg extension regimen. Findings Ingestion of β-glucans, but not placebo, protected against inflammation based on subjective soreness scores (two trials), as well as on plasma myeloperoxidase readings (one trial). Scores were subject ratings from 0 (no soreness) to 10 (injury that impairs movement). Mean soreness score was lower at 48 h after exercise stress: post-glucan treatment vs pre-treatment: Trial 1: 1.9 + 2.4 vs 3.3 + 2.2 (p = 0.05); Trial 2: 1.2 + 0.7 vs 3.9 + 2.7 (p < 0.05). Myeloperoxidase just after exercise stress increased for both groups pre-treatment, but only for the placebo group post-treatment: 62 + 12 vs 81 + 15 (p < 0.05). Originality/value This pilot study found that at least one type of dietary fiber can exert anti-inflammatory effects in skeletal muscle.