Accumulation of pyrophosphate in Escherichia coli. Relationship to growth and nucleotide synthesis

Pyrophosphate (PPi) content of Escherichia coli is increased manyfold when the growth of the cells is limited by inhibition of the synthesis of nucleotides. The accumulated PPi is immediately degraded when inhibition is released and growth allowed to resume. Other tested nutritional deficiencies (st...

Full description

Saved in:
Bibliographic Details
Published inArchives of microbiology Vol. 136; no. 3; p. 209
Main Authors Kukko, E, Saarento, H
Format Journal Article
LanguageEnglish
Published Germany 01.11.1983
Subjects
Diphosphates - metabolism
Escherichia coli - growth & development
Escherichia coli - metabolism
Nucleotides - biosynthesis
Purines - metabolism
Pyrimidines - metabolism
Online AccessGet more information

Cover

More Information
Summary:Pyrophosphate (PPi) content of Escherichia coli is increased manyfold when the growth of the cells is limited by inhibition of the synthesis of nucleotides. The accumulated PPi is immediately degraded when inhibition is released and growth allowed to resume. Other tested nutritional deficiencies (starvation of carbon source, sulfate or an amino acid) fail to induce PPi accumulation.
ISSN:0302-8933
DOI:10.1007/BF00409846