Primary spinal malignant schwannoma: clinical, histological and cytogenetic findings

Of the 19 patients who presented between 1980 and 1990 to the Department of Neurosurgery, University of Hamburg, F. R. G. with malignant schwannoma, 5 patients suffered from primary malignant spinal schwannoma (mean age 44 years, only one patient with von Recklinghausen's disease). Here we repo...

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Bibliographic Details
Published inNeurosurgical review Vol. 14; no. 4; p. 283
Main Authors Valdueza, J M, Hagel, C, Westphal, M, Hänsel, M, Herrmann, H D
Format Journal Article
LanguageEnglish
Published Germany 01.01.1991
Subjects
Adolescent
Adult
Aged
Biomarkers, Tumor - analysis
Chromosome Aberrations - genetics
Female
Humans
Karyotyping
Magnetic Resonance Imaging
Male
Middle Aged
Neurilemmoma - genetics
Neurilemmoma - pathology
Neurofibromatosis 1 - genetics
Neurofibromatosis 1 - pathology
Spinal Cord - pathology
Spinal Cord Compression - genetics
Spinal Cord Compression - pathology
Spinal Cord Neoplasms - genetics
Spinal Cord Neoplasms - pathology
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Summary:Of the 19 patients who presented between 1980 and 1990 to the Department of Neurosurgery, University of Hamburg, F. R. G. with malignant schwannoma, 5 patients suffered from primary malignant spinal schwannoma (mean age 44 years, only one patient with von Recklinghausen's disease). Here we report the clinical, histological, and cytogenetic features of the five cases with primary malignant spinal schwannoma and discuss the prognostic aspects of this rare tumor.
ISSN:0344-5607
DOI:10.1007/BF00383263