Clinical significance of E-Cadherin and β-catenin in early gastric cancer: A protocol of systematic review

This study will summarize the clinical significance of E-Cadherin and β-catenin in early gastric cancer (EGC). Eligible case-control studies were searched from Cochrane Library, PUBMED, EMBASE, PsycINFO, Google Scholar, CBM, and CNKI from inception to the present. In addition, we will also search ot...

Full description

Saved in:
Bibliographic Details
Published inMedicine (Baltimore) Vol. 99; no. 41; p. e22271
Main Authors Zhang, Shu-Fen, Zhang, Jian-Hua
Format Journal Article
LanguageEnglish
Published United States Lippincott Williams & Wilkins 09.10.2020
Subjects
beta Catenin - metabolism
Biomarkers, Tumor - metabolism
Cadherins - metabolism
Humans
Research Design
Stomach Neoplasms - metabolism
Study Protocol Systematic Review
Systematic Reviews as Topic
Online AccessGet full text

Cover

More Information
Summary:This study will summarize the clinical significance of E-Cadherin and β-catenin in early gastric cancer (EGC). Eligible case-control studies were searched from Cochrane Library, PUBMED, EMBASE, PsycINFO, Google Scholar, CBM, and CNKI from inception to the present. In addition, we will also search other sources to avoid missing potential studies. Two authors will independently carry out study selection, data collection, and study methodological quality. A fixed or random-effects model will be utilize to synthesize the data, and RevMan 5.3 software will be used for data analysis. This study will summarize all eligible studies to investigate the clinical significance of E-Cadherin and β-catenin in EGC. The findings of this study may present a genuine understanding of perspective on the clinical significance of E-Cadherin and β-catenin in EGC.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
This study was supported by Yan’an Specialized Project for Transformation and Promotion of Achievements (2018CGZH-15). The supported was not allowed to involve any sections of this study.
Data sharing not applicable to this article as no datasets were generated or analyzed during the current study.
The authors have no conflicts of interests to disclose.
INPLASY202080072.
How to cite this article: Zhang Sf, Zhang Jh. Clinical significance of E-Cadherin and β-catenin in early gastric cancer: A protocol of systematic review. Medicine. 2020;99:41(e22271).
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000022271