What’s the n? On sample size vs. subject number for brain-behavior neurophysiology and neuromodulation

• Published in: Neuron (Cambridge, Mass.) Vol. 112; no. 13; pp. 2086 - 2090
• Main Authors: Asaad, Wael F., Sheth, Sameer A.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 03.07.2024
• ISSN: 0896-6273; 1097-4199; 1097-4199
• DOI: 10.1016/j.neuron.2024.04.033

Neurophysiology and neuromodulation strive to understand the neural basis of behavior through a one-to-one correspondence between a particular brain and its behavioral output. Within this framework, studies with few subjects but sufficient sample sizes can be both rigorous and impactful. Neurophysiology and neuromodulation strive to understand the neural basis of behavior through a one-to-one correspondence between a particular brain and its behavioral output. Within this framework, studies with few subjects but sufficient sample sizes can be both rigorous and impactful.