An innovative radio-guided surgery technique for complete resection of tumors

• Published in: Journal of physics. Conference series Vol. 566; no. 1; pp. 12020 - 6
• Main Authors: Russomando, A, Collamati, F, Bellini, F, Bocci, V, Lucia, E De, Faccini, R, Frallicciardi, P M, Marafini, M, Mattei, I, Morganti, S, Patera, V, Piersanti, L, Pinci, D, Recchia, L, Senzacqua, M, Sarti, A, Sciubba, A, Camillocci, E Solfaroli, Voena, C
• Format: Journal Article
• Language: English
• Published: Bristol IOP Publishing 01.01.2014
• Subjects: Background radiation; Constraining; Devices; Diffusion; Gamma rays; Life expectancy; Patients; Photons; Physics; Radio; Surgery; Tumors
• ISSN: 1742-6588; 1742-6596
• DOI: 10.1088/1742-6596/566/1/012020

Finding new ways to fight cancer is essential to increase the patients life expectancy. This paper reports the latest results of the project CHIRONE finalized to increase the potential of the Radio Guided Surgery through the use of β− emitting radio-tracers and β− probes. This innovation could overcome the present main limiting factor represented by a diffuse background due to the high penetration power of the gamma radiation used. We created a prototype of β− probe and in this paper we report measures of photon efficiency, acquired with commercial photons sources. Then we estimated the signal and background rates in realistic cases of meningioma through a simulation. The device is able to detect residuals of 0.1 ml in 1 s with an administered activity less than 3 MBq/kg.