Improved grading of bone tumors with the monoclonal antibody Ki-67

A total of 60 bone tumors and tumor-like lesions presenting various grades of malignancy were investigated immunohistologically with the monoclonal antibody Ki-67 directed against a cell proliferation-associated nuclear antigen. The results obtained agree well with those of flow cytometric and autor...

Full description

Saved in:
Bibliographic Details
Published inJournal of cancer research and clinical oncology Vol. 112; no. 3; p. 281
Main Authors Vollmer, E, Roessner, A, Gerdes, J, Mellin, W, Stein, H, Chong-Schachel, S, Grundmann, E
Format Journal Article
LanguageEnglish
Published Germany 01.01.1986
Subjects
Antibodies, Monoclonal
Bone and Bones - pathology
Bone Neoplasms - pathology
Cell Division
Humans
Immunoenzyme Techniques
Neoplasm Staging
Online AccessGet more information

Cover

More Information
Summary:A total of 60 bone tumors and tumor-like lesions presenting various grades of malignancy were investigated immunohistologically with the monoclonal antibody Ki-67 directed against a cell proliferation-associated nuclear antigen. The results obtained agree well with those of flow cytometric and autoradiographic studies on similar tumor entities. The monoclonal antibody Ki-67 was found to be a handy and reliable tool for improved grading of bone tumors.
ISSN:0171-5216
DOI:10.1007/BF00395924