Growth inhibitory effect of antibiotic tetaine on yeast and mycelial forms of Candida albicans
The mycelial (M) form of Candida albicans is more sensitive to the action of the antibiotic tetaine than the yeast (Y) form. Tetaine, at low concentrations about 1 microgram/ml also inhibits Y-M transition. It causes severe deformation of cells, agglutination and inhibits septum formation in the yea...
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Published in | Archives of microbiology Vol. 135; no. 2; p. 130 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Germany
01.08.1983
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Subjects | |
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Abstract | The mycelial (M) form of Candida albicans is more sensitive to the action of the antibiotic tetaine than the yeast (Y) form. Tetaine, at low concentrations about 1 microgram/ml also inhibits Y-M transition. It causes severe deformation of cells, agglutination and inhibits septum formation in the yeast forms. Tetaine action is reversed by dipeptides in both forms and by tripeptides in M form. N-acetyl glucosamine is a powerful antagonist of tetaine action on both morphological forms. Tetaine action on mycelial forms is slightly antagonised by N-acetyl mannosamine and very powerfully by glutamine. |
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AbstractList | The mycelial (M) form of Candida albicans is more sensitive to the action of the antibiotic tetaine than the yeast (Y) form. Tetaine, at low concentrations about 1 microgram/ml also inhibits Y-M transition. It causes severe deformation of cells, agglutination and inhibits septum formation in the yeast forms. Tetaine action is reversed by dipeptides in both forms and by tripeptides in M form. N-acetyl glucosamine is a powerful antagonist of tetaine action on both morphological forms. Tetaine action on mycelial forms is slightly antagonised by N-acetyl mannosamine and very powerfully by glutamine. |
Author | Borowski, E Milewski, S Chmara, H |
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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/6357134$$D View this record in MEDLINE/PubMed |
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CitedBy_id | crossref_primary_10_1111_j_1574_6968_1991_tb04496_x crossref_primary_10_1016_0167_4781_85_90104_6 crossref_primary_10_1111_j_1574_6968_1991_tb04495_x crossref_primary_10_1016_j_ejps_2015_12_013 crossref_primary_10_3109_10408418709104437 crossref_primary_10_1016_S0167_4838_02_00318_7 crossref_primary_10_1111_j_1574_6968_2004_tb09569_x crossref_primary_10_1021_acs_jnatprod_9b00110 crossref_primary_10_1111_j_1574_6968_1990_tb13995_x crossref_primary_10_1016_0167_4838_85_90304_8 crossref_primary_10_1111_j_1574_6968_1985_tb00763_x crossref_primary_10_1007_BF00443651 crossref_primary_10_1007_BF01575593 crossref_primary_10_1111_j_1574_6968_1988_tb02914_x crossref_primary_10_1002_yea_1337 crossref_primary_10_1128_jb_178_8_2320_2327_1996 |
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Snippet | The mycelial (M) form of Candida albicans is more sensitive to the action of the antibiotic tetaine than the yeast (Y) form. Tetaine, at low concentrations... |
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SubjectTerms | Amino Acids - pharmacology Amino Sugars - pharmacology Anti-Bacterial Agents - pharmacology Candida albicans - cytology Candida albicans - drug effects Candida albicans - growth & development Dipeptides - pharmacology Peptides - pharmacology |
Title | Growth inhibitory effect of antibiotic tetaine on yeast and mycelial forms of Candida albicans |
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