Amanita phalloides poisoning-induced end-stage renal failure

Fungi poisoning is quite frequent: in particular, Amanita phalloides has life-threatening toxicity. It is responsible for fulminant hepatitis, and also has renal toxicity. Herein, we report on a patient who developed acute renal failure after ingesting A. phalloides, which required definitive renal...

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Bibliographic Details
Published inClinical nephrology Vol. 71; no. 5; p. 571
Main Authors Garrouste, C, Hémery, M, Boudat, A M, Kamar, N
Format Journal Article
LanguageEnglish
Published Germany 01.05.2009
Subjects
Aged
Amanita - isolation & purification
Amanita - pathogenicity
Biopsy
Diagnosis, Differential
Female
Humans
Kidney - pathology
Kidney Failure, Chronic - diagnosis
Kidney Failure, Chronic - etiology
Kidney Failure, Chronic - therapy
Mushroom Poisoning - complications
Mushroom Poisoning - diagnosis
Renal Dialysis - methods
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Summary:Fungi poisoning is quite frequent: in particular, Amanita phalloides has life-threatening toxicity. It is responsible for fulminant hepatitis, and also has renal toxicity. Herein, we report on a patient who developed acute renal failure after ingesting A. phalloides, which required definitive renal replacement therapy, despite rapid liver injury recovery. A kidney biopsy showed massive acute tubular necrosis, mainly in the proximal convoluted tubule, and mild interstitial infiltration by mononuclear cells.
ISSN:0301-0430
DOI:10.5414/CNP71571