MicroRNAs as biomarkers for dental diseases

MicroRNAs (miRNAs) are short, noncoding RNAs that act as key regulators of diverse biological processes by mediating translational repression or mRNA degradation of target genes. Recent studies discovered miRNAs in saliva, and these miRNAs are promising candidates for use as biomarkers of dental dis...

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Published inSingapore dental journal Vol. 36; pp. 18 - 22
Main Authors Kim, Su-Hwan, Lee, Su-Yeon, Lee, Yong-Moo, Lee, Young-Kyoo
Format Journal Article
LanguageEnglish
Published Singapore Elsevier B.V 01.12.2015
Subjects
Biomarker
Dentistry
microRNA
Periodontitis
Saliva
microRNA
Biomarker
Periodontitis
Saliva
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Summary:MicroRNAs (miRNAs) are short, noncoding RNAs that act as key regulators of diverse biological processes by mediating translational repression or mRNA degradation of target genes. Recent studies discovered miRNAs in saliva, and these miRNAs are promising candidates for use as biomarkers of dental diseases. In this review, the results of miRNA studies in the dental field are presented, and a brief overview of the current progress, limitations, and perspectives regarding miRNA biomarkers for dental diseases is given.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ISSN:0377-5291
DOI:10.1016/j.sdj.2015.09.001