Uterine size and volume are associated with higher live birth rate in patients undergoing assisted reproduction technology: A prospective cohort study

• Published in: Medicine (Baltimore) Vol. 98; no. 47; p. e17966
• Main Authors: Gao, Hong, Liu, Dong-E, Li, Yumei, Tang, Jing, Wu, Xinrui, Tan, Hongzhuan
• Format: Journal Article
• Language: English
• Published: United States Wolters Kluwer Health 01.11.2019
• Subjects: Adult; Birth Rate; Cohort Studies; Female; Humans; Live Birth; Observational Study; Organ Size; Pregnancy; Prospective Studies; Reproductive Techniques, Assisted; Uterus - anatomy & histology
• ISSN: 0025-7974; 1536-5964
• DOI: 10.1097/MD.0000000000017966

To investigate how uterine size and volume are associated with live birth rate in patients undergoing assisted reproduction technology.This prospective cohort study was conducted at the Reproductive Medicine Centre from January 2010 to May 2017. Multivariate binary logistic regression was used to evaluate the relations between uterine size, total volume, and live birth outcomes, after they were adjusted for the main influencing factors.A total of 7320 women of clinical pregnancy were enrolled. Compared with uterine lengths of 50 to 59 mm (referent), women with uterine lengths ≥60 mm had a lower live birth rate (RR = 1.541). Compared with uterine widths of ≥50 mm (referent), women with uterine widths <30 mm had a lower live birth rate (RR = 1.430). Compared with uterine anteroposterior diameters of <30 mm (referent), women with uterine anteroposterior diameters ≥50 mm had a lower live birth rate (RR = 1.636). Compared with uterine volumes of 30 to 49 mL (referent), women with volumes <30 mL and ≥70 mL had lower live birth rates (RR = 1.368 and 1.742, respectively).Our findings indicate that uterine sizes and volumes that were too large or too small reduced the live birth rate.