Enhanced external counterpulsation increases coronary flow reserve in coronary microvascular disease

To investigates the outcomes of enhanced external counterpulsation (EECP) among coronary microvascular disease (CMD) patients. Coronary microvascular disease patients were separated into the EECP (n=41) and control cohorts (n=42). Prior to and following the 4-week EECP program, coronary flow reserve...

Full description

Saved in:
Bibliographic Details
Published inSaudi medical journal Vol. 44; no. 12; pp. 1277 - 1282
Main Authors Wang, Qian, Hao, Jia, Jiang, Wenjun, Tan, Qiang
Format Journal Article
LanguageEnglish
Published Saudi Arabia 01.12.2023
Subjects
Angina Pectoris
Canada
Counterpulsation
Endothelin-1
Humans
Quality of Life
Treatment Outcome
Canada
endothelial function
enhanced external counterpulsation
coronary flow reserve
coronary microvascular disease
Online AccessGet full text

Cover

More Information
Summary:To investigates the outcomes of enhanced external counterpulsation (EECP) among coronary microvascular disease (CMD) patients. Coronary microvascular disease patients were separated into the EECP (n=41) and control cohorts (n=42). Prior to and following the 4-week EECP program, coronary flow reserve (CFR) was recorded using transthoracic Doppler echocardiography. The serum endothelial nitric oxide synthase (eNOS) and endothelin-1 (ET-1) contents were analyzed by ELISA. Quality of life (QoL) was assessed by the Seattle Angina Questionnaire (SAQ) and the Canadian Cardiovascular Society (CCS) angina class. After four weeks, CFR was substantially enhanced in the EECP versus control cohort ( <0.05). Endothelin-1 was strongly diminished whereas eNOS was considerably upregulated in the EECP cohort. EECP also enhanced patients' SAQ scores and decreased the CCS angina class. Enhanced external counterpulsation may improve CFR and enhance the CMD patient QoL.
ISSN:0379-5284
1658-3175
DOI:10.15537/smj.2023.44.12.20230427