Extraction of colchicine from Gloriosa superba tubers: a comparison of conventional and microwave-assisted extraction

The present work envisages assessment of microwave assisted extraction (MAE) followed by comparison with that of conventional methods for effective extraction of colchicine from Gloriosa superba tubers. Subsequently, optimum conditions for MAE were determined using response surface methodology by em...

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Bibliographic Details
Published inThe Journal of microwave power and electromagnetic energy Vol. 53; no. 1; pp. 57 - 66
Main Authors Agrawal, Poonam, Laddha, Kirti
Format Journal Article
LanguageEnglish
Published Taylor & Francis 02.01.2019
Subjects
Box-Behnken design
Colchicine
conventional
Gloriosa superba
microwave extraction
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Summary:The present work envisages assessment of microwave assisted extraction (MAE) followed by comparison with that of conventional methods for effective extraction of colchicine from Gloriosa superba tubers. Subsequently, optimum conditions for MAE were determined using response surface methodology by employing Box-Behnken design. The observed optimal conditions for efficient extraction of colchicine using microwave were 15 min, 245 W and 100% methanol which showed 0.64% colchicine as compared to conventional with 0.48% by heat reflux extraction. Assessment of extraction techniques revealed that significant amount of time and energy could be saved using MAE, whilst lesser amount of organic solvent consumption showed an eco-friendly nature.
ISSN:0832-7823
2472-4041
DOI:10.1080/08327823.2019.1570450