Synthesis, crystal structure, and insulin-like activity of [N′-(2-hydroxy-3-methoxybenzylidene)-2-methoxybenzohydrazonato](1,10-phenanthroline)oxovanadium(IV) methanol solvate

• Published in: Inorganic and nano-metal chemistry Vol. 47; no. 11; pp. 1585 - 1589
• Main Authors: Meng, Xu-Feng, Liu, Qi-Feng, Liu, Ji-Lai, Sun, Ming-Hui, Ma, Jing-Jun
• Format: Journal Article
• Language: English
• Published: Taylor & Francis 02.11.2017
• Subjects: aroylhydrazone; crystal structure; insulin-like activity; thermal property; Vanadium complex
• ISSN: 2470-1556; 2470-1564
• DOI: 10.1080/24701556.2017.1357613

The aroylhydrazone Schiff base ligand N′-(2-hydroxy-3-methoxybenzylidene)-2-methoxybenzohydrazide (H 2 L) reacts with VO(acac) 2 and 1,10-phenanthroline (Phen) in methanol to give the complex [N′-(2-hydroxy-3-methoxybenzylidene)-2-methoxybenzohydrazonato](1,10-phenanthroline)oxovanadium(IV) methanol solvate, [V IV OL(Phen)]·CH 3 OH. The structure of the complex was characterized by elemental analyses and IR spectroscopic method in the solid state. Single-crystal X-ray analysis was also performed. The complex crystallized in the triclinic space group P-1, with unit cell dimensions a = 9.220(3) Å, b = 9.382(3) Å, c = 16.593(5) Å, α = 73.900(5)°, β = 78.618(6)°, γ = 84.959(6)°, V = 1351.1(7) Å 3 , Z = 2, R 1 = 0.0837, and wR 2 = 0.0751. The vanadium(V) atom in the complex is six-coordinated with an octahedral geometry. Thermal stability as well as the insulin-like activity of the complex have been determined.