Dual infection with dengue virus 3 and human immunodeficiency virus 1 in Havana, Cuba

Although dengue virus (DEN) endemic regions overlap with human immunodeficiency virus 1 (HIV) high incidence areas, little has been documented on HIV and DEN mixed infection. Here we report DEN/HIV concurrent infections recorded during the DEN-3 epidemic in 2001-2002 in Havana. Serologic-confirmed D...

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Bibliographic Details
Published inJournal of infection in developing countries Vol. 3; no. 4; pp. 318 - 320
Main Authors Gonzalez, Daniel, Limonta, Daniel, Bandera, Juan Francisco, Perez, Jorge, Kouri, Gustavo, Guzman, Maria G
Format Journal Article
LanguageEnglish
Published Italy Journal of Infection in Developing Countries 01.05.2009
Subjects
Adult
Case reports
CD4 Lymphocyte Count
Cuba
Dengue - complications
Dengue - diagnosis
Dengue - epidemiology
Dengue fever
Dengue Virus - isolation & purification
HIV
HIV Infections - complications
HIV Infections - diagnosis
HIV-1 - isolation & purification
Human immunodeficiency virus
Humans
Immune system
Infections
Male
Viral infections
Young Adult
Cuba
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Summary:Although dengue virus (DEN) endemic regions overlap with human immunodeficiency virus 1 (HIV) high incidence areas, little has been documented on HIV and DEN mixed infection. Here we report DEN/HIV concurrent infections recorded during the DEN-3 epidemic in 2001-2002 in Havana. Serologic-confirmed DEN is described in two HIV-infected subjects with dengue fever symptoms. Although patients had dengue disease, the CD4+ cells remained within normal levels and no accelerated progression of HIV disease was observed. To our knowledge, DEN cases caused by DEN-3 in HIV-infected individuals have not been reported previously. Further research is needed to diagnose this likely underreported mixed viral infection in DEN endemic areas.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
ObjectType-Article-3
ISSN:2036-6590
1972-2680
DOI:10.3855/jidc.131