Efficacy of Yiqi Wenyang Huoxue method in treating adult bronchial asthma: A protocol for systematic review and meta-analysis of randomized controlled trials

• Published in: Medicine (Baltimore) Vol. 101; no. 9; p. e28958
• Main Authors: Yu, Qiangqiang, Bao, Mengjie, Yu, Tao, Zhang, Yuanbing, Xiang, Shuangdi, Li, Tao, Sun, Peng, Ye, Chao, Shen, Jianli, Yu, Jianwei, Xue, Hanrong
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 04.03.2022
• Subjects: Asthma - drug therapy; Drugs, Chinese Herbal - therapeutic use; Humans; Medicine, Chinese Traditional - methods; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Study Protocol Systematic Review; Systematic Reviews as Topic; Treatment Outcome
• ISSN: 0025-7974; 1536-5964; 1536-5964
• DOI: 10.1097/MD.0000000000028958

Bronchial asthma (BA) is a chronic inflammatory disease of the airway, which has the characteristics of recurrent attacks and difficult to cure. Glucocorticoid and bronchodilator are the primary treatment drugs for asthma. Although the treatment has made some progress, the control status is still not ideal. According to clinical reports, the Yi-qi Wen-yang Huo-xue method (YQWYHXM) of Traditional Chinese Medicine (TCM) is safe and effective in the treatment of BA, but there is not enough evidence to prove it. Based on it, we conducted this systematic evaluation. Eight databases and Clinical trial registries (Embase, Cochrane, PubMed, CNKI, CBM, Wanfang, VIP, China Clinical Trial Registry and Clinical Trails) were searched from the establishment of those until January 22, 2021 with the following terms for retrieval: BS, TCM, Chinese medicinal herb, Chinese herbal medicine and randomized controlled trial. Data analysis was performed by 2 researchers using RevMan 5.3 and SATA 16.0 separately from the Cochrane Collaboration. This study will be able to provide definitive evidence to clarify all the suspicions we seek, confirming the effectiveness of YQWYHXM in the treatment of adults with BA. This study will prove that YQWYHXM is a safe and effective TCM adjuvant therapy for BA. Efficacy of Yiqi Wenyang Huoxue method in Treating Adult Bronchial Asthma. A protocol for Systematic Review and Meta-Analysis of Randomized Controlled Trials. PROSPERO 2021 CRD42021256791. Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021256791.