Therapeutic effect of human recombinant interferon-alpha-2C in essential thrombocythaemia

Human recombinant interferon-alpha 2C was given to 4 patients with essential thrombocythaemia. Three patients achieved a complete remission on day 19 +/- 1 and the 4th achieved a partial remission. After 4 weeks of induction therapy, a maintenance therapy of twice weekly intramuscular injections of...

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Published inOncology Vol. 42 Suppl 1; p. 10
Main Authors Velu, T, Delwiche, F, Gangji, D, Monsieur, R, Flament, J, Stryckmans, P, Wybran, J, Bellens, R
Format Journal Article
LanguageEnglish
Published Switzerland 1985
Subjects
Aged
Female
Humans
Interferon Type I - therapeutic use
Male
Middle Aged
Platelet Count
Recombinant Proteins - therapeutic use
Thrombocythemia, Essential - therapy
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Summary:Human recombinant interferon-alpha 2C was given to 4 patients with essential thrombocythaemia. Three patients achieved a complete remission on day 19 +/- 1 and the 4th achieved a partial remission. After 4 weeks of induction therapy, a maintenance therapy of twice weekly intramuscular injections of 5 X 10(6) or 10 X 10(6) IU was instituted but did not maintain the remission.
ISSN:0030-2414
DOI:10.1159/000226078