Influenza vaccination and the activities of plasma acetylcholinesterase and butyrylcholinesterase in institutionalised elderly patients

Influenza immunisation was given to 30 elderly institutionalised patients (mean age 80 years) and 16 young volunteers (mean age 27 years). Blood was taken at days 0, 2, 7 and 28. Plasma butyrylcholinesterase (BuChE) and acetylcholinesterase (ACHE) activities were measured. The activities of both enz...

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Published inArchives of gerontology and geriatrics Vol. 27; no. 2; pp. 179 - 185
Main Authors Emam, Seyed Jalal, O'Mahony, M.Sinead, El Khatieb, Mustafa, Edwards, Nia, Woodhouse, Ken
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ireland Ltd 01.09.1998
Subjects
Acetylcholinesterase
Ageing
Butyrylcholinesterase
Drug metabolism
Influenza immunisation
Drug metabolism
Influenza immunisation
Acetylcholinesterase
Butyrylcholinesterase
Ageing
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Summary:Influenza immunisation was given to 30 elderly institutionalised patients (mean age 80 years) and 16 young volunteers (mean age 27 years). Blood was taken at days 0, 2, 7 and 28. Plasma butyrylcholinesterase (BuChE) and acetylcholinesterase (ACHE) activities were measured. The activities of both enzymes were lower in the elderly patients compared to the young volunteers ( P<0.001); however, influenza vaccination had no effect on either enzyme, in either age group.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0167-4943
1872-6976
DOI:10.1016/S0167-4943(98)00113-7