Cupin-domain containing protein is not essential for the alkyl salicylaldehyde formation in Aspergillus ustus

• Published in: Chemical communications (Cambridge, England) Vol. 60; no. 81; pp. 11556 - 11559
• Main Authors: Peter, Marlies, Li, Shu-Ming
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 08.10.2024
• Subjects: Aldehydes - chemistry; Aldehydes - metabolism; Aspergillus - chemistry; Aspergillus - metabolism; Fungal Proteins - chemistry; Fungal Proteins - genetics; Fungal Proteins - metabolism; Molecular Structure; Protein Domains

Previous studies demonstrated the requirement of four enzymes including a cupin-domain containing protein for the formation of alkyl salicylaldehydes and derivatives. Heterologous expression of three biosynthetic genes from Aspergillus ustus resulted in the formation of such compounds in high-yields...