Cupin-domain containing protein is not essential for the alkyl salicylaldehyde formation in Aspergillus ustus

Previous studies demonstrated the requirement of four enzymes including a cupin-domain containing protein for the formation of alkyl salicylaldehydes and derivatives. Heterologous expression of three biosynthetic genes from Aspergillus ustus resulted in the formation of such compounds in high-yields...

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Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 60; no. 81; pp. 11556 - 11559
Main Authors Peter, Marlies, Li, Shu-Ming
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 08.10.2024
Subjects
Aldehydes - chemistry
Aldehydes - metabolism
Aspergillus - chemistry
Aspergillus - metabolism
Fungal Proteins - chemistry
Fungal Proteins - genetics
Fungal Proteins - metabolism
Molecular Structure
Protein Domains
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Summary:Previous studies demonstrated the requirement of four enzymes including a cupin-domain containing protein for the formation of alkyl salicylaldehydes and derivatives. Heterologous expression of three biosynthetic genes from Aspergillus ustus resulted in the formation of such compounds in high-yields without involvement of a cupin analogue.
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ISSN:1359-7345
1364-548X
1364-548X
DOI:10.1039/D4CC04227A