(Z)-1-Benzyl-5-(4-bromophenyl)-5-hydroxy-4-(2-oxomorpholin-3-ylidene)pyrrolidine-2,3-dione

The reaction of 8-(4-bromobenzoyl)-3,4-dihydro-1H-pyrrolo[2,1-c][1,4]oxazine-1,6,7-trione with benzylamine in acetonitrile at room temperature afforded a good yield of (Z)-1-benzyl-5-(4-bromophenyl)-5-hydroxy-4-(2-oxomorpholin-3-ylidene)pyrrolidine-2,3-dione. The compound was fully characterized.

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Bibliographic Details
Published inMolBank Vol. 2023; no. 4; p. M1751
Main Authors Tretyakov, Nikita A., Maslivets, Andrey N.
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.12.2023
Subjects
1,4-oxazine
Acetonitrile
Analgesics
Conflicts of interest
Crystal structure
Diketones
heterocyclization
Mineral oils
Pharmaceutical industry
pyrrolidine
pyrrolidine-2,3-dione
Room temperature
Poland
United States > US
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Summary:The reaction of 8-(4-bromobenzoyl)-3,4-dihydro-1H-pyrrolo[2,1-c][1,4]oxazine-1,6,7-trione with benzylamine in acetonitrile at room temperature afforded a good yield of (Z)-1-benzyl-5-(4-bromophenyl)-5-hydroxy-4-(2-oxomorpholin-3-ylidene)pyrrolidine-2,3-dione. The compound was fully characterized.
ISSN:1422-8599
1422-8599
DOI:10.3390/M1751