Synthesis, crystal structures, and biological activity of zinc(II) complexes derived from 2-amino-1,3,4-thiadiazole derivatives

Two new similar zinc(II) complexes, [ZnCl 2 L1 2 ] and [ZnCl 2 L2 2 ], derived from the 2-amino-1,3,4-thiadiazole derivatives, were prepared and structurally characterized by X-ray diffraction. The Zn atom in each complex has a tetrahedral coordination and is coordinated by two N atoms of the ligand...

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Published inInorganic and nano-metal chemistry Vol. 47; no. 1; pp. 78 - 81
Main Authors Zhu, Hui-Long, Liu, Yu-Wei, Tang, Zong-Ming, Yin, Fu-Jun, Liu, Wei-Wei, Cao, Zhi-Ling, Bao, Juan, Li, Meng, Qin, Ling-Yan, Shi, Da-Hua
Format Journal Article
LanguageEnglish
Published Taylor & Francis 02.01.2017
Subjects
1,3,4-Thiadiazole derivatives
crystal structure
urease inhibition
zinc
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Summary:Two new similar zinc(II) complexes, [ZnCl 2 L1 2 ] and [ZnCl 2 L2 2 ], derived from the 2-amino-1,3,4-thiadiazole derivatives, were prepared and structurally characterized by X-ray diffraction. The Zn atom in each complex has a tetrahedral coordination and is coordinated by two N atoms of the ligands and two Cl atoms. The urease inhibitory activities of the complexes and the ligands were evaluated.
ISSN:2470-1556
2470-1564
DOI:10.1080/15533174.2016.1149723