Carbon nanotube–chitosan modified disposable pencil graphite electrode for Vitamin B₁₂ analysis

• Published in: Colloids and surfaces, B, Biointerfaces Vol. 87; no. 1; pp. 18 - 22
• Main Authors: Kuralay, Filiz, Vural, Tayfun, Bayram, Cem, Denkbas, Emir Baki, Abaci, Serdar
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.10.2011
• Subjects: Carbon; chitosan; Chitosan - chemistry; colloids; Dielectric Spectroscopy; Disposable Equipment; drugs; Electrochemical Techniques; electrochemistry; Electrodes; graphene; Graphite; Graphite - chemistry; Hydrogen-Ion Concentration; Nanocomposites; Nanomaterials; Nanostructure; Nanotubes, Carbon - chemistry; Nanotubes, Carbon - ultrastructure; Pencils; scanning electron microscopy; Vitamin B 12 - analysis; Vitamin B12
• ISSN: 0927-7765; 1873-4367
• DOI: 10.1016/j.colsurfb.2011.03.030

A single walled carbon nanotube–chitosan (SWCNT–chitosan) modified disposable pencil graphite electrode (PGE) was used in this study for the electrochemical detection of Vitamin B₁₂. Electrochemical behaviors of SWCNT–chitosan PGE and chitosan modified PGE were compared by using cyclic voltammetry (CV), square-wave voltammetry (SWV) and electrochemical impedance spectroscopy (EIS) techniques. SWCNT–chitosan modified electrode was also used for the quantification of Vitamin B₁₂ in pharmaceutical products. The results show that this electrode system is suitable for sensitive Vitamin B₁₂ analysis giving good recovery results. The surface morphologies of the SWCNT–chitosan PGE, chitosan modified PGE and unmodified PGE were characterized by using scanning electron microscopy (SEM).