Candidosis of the urinary tract with padding phenomenon of the renal pelvises in an infant with obstructive uropathy

A male infant with obstructive uropathy developed yeast cell agglomerations which were detectable macroscopically and by image-generating techniques within both renal pelvises after Candida albicans infection of the urinary tract. Therapy with flucytosine induced excretion of 'fungal balls'...

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Bibliographic Details
Published inMycoses Vol. 37; no. 7-8; p. 291
Main Authors Walther, F, Kaben, U, Radke, M, Terpe, R, Stolpe, H J
Format Journal Article
LanguageEnglish
Published Germany 01.07.1994
Subjects
Amphotericin B - administration & dosage
Candidiasis - complications
Candidiasis - diagnosis
Candidiasis - drug therapy
Flucytosine - therapeutic use
Humans
Infant
Liposomes
Male
Urethral Obstruction - complications
Urologic Diseases - complications
Urologic Diseases - diagnosis
Urologic Diseases - drug therapy
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Summary:A male infant with obstructive uropathy developed yeast cell agglomerations which were detectable macroscopically and by image-generating techniques within both renal pelvises after Candida albicans infection of the urinary tract. Therapy with flucytosine induced excretion of 'fungal balls' via the urethra. Continuation of therapy with liposomal amphotericin B (AmBisome) prevented a relapse after development of fungal resistance against flucytosine. Sonographically or radiographically detectable formation of 'concrements' within the urinary tract of patients with an immature or compromised immune system and additional features such as obstructive urinary tract should suggest a localized or systemic mycosis, particularly in the context of long-term antibiotic treatment.
ISSN:0933-7407
DOI:10.1111/j.1439-0507.1994.tb00429.x