Statin Effects on Vascular Calcification: Microarchitectural Changes in Aortic Calcium Deposits in Aged Hyperlipidemic Mice

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Bibliographic Details
Published inArteriosclerosis, thrombosis, and vascular biology Vol. 41; no. 4; pp. e185 - e192
Main Authors Xian, Joshua Zhaojun, Lu, Mimi, Fong, Felicia, Qiao, Rong, Patel, Nikhil Rajesh, Abeydeera, Dishan, Iriana, Sidney, Demer, Linda L, Tintut, Yin
Format Journal Article
LanguageEnglish
Published United States 01.04.2021
Subjects
Age Factors
Animals
Aorta - diagnostic imaging
Aorta - drug effects
Aorta - metabolism
Aorta - pathology
Aortic Diseases - diagnostic imaging
Aortic Diseases - drug therapy
Aortic Diseases - metabolism
Aortic Diseases - pathology
Atherosclerosis - diagnostic imaging
Atherosclerosis - drug therapy
Atherosclerosis - metabolism
Atherosclerosis - pathology
Calcium - metabolism
Disease Models, Animal
Female
Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology
Hyperlipidemias - blood
Hyperlipidemias - drug therapy
Lipids - blood
Mice
Mice, Inbred C57BL
Mice, Knockout, ApoE
Plaque, Atherosclerotic
Pravastatin - pharmacology
Rupture, Spontaneous
Time Factors
Vascular Calcification - diagnostic imaging
Vascular Calcification - drug therapy
Vascular Calcification - metabolism
Vascular Calcification - pathology
atherosclerosis
pravastatin
vascular calcification
aging
artery
positron emission tomography
vascular
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Summary:[Figure: see text].
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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Present address: St. Agnes Medical Center, Fresno, California
ISSN:1079-5642
1524-4636
DOI:10.1161/ATVBAHA.120.315737