Chemical constituent with cytotoxicity from Sterculia diversifolia

One new coumarin (stercularin), along with eleven known compounds, was isolated for the first time from ethyl acetate fraction of Sterculia diversifolia. The structures of isolated compounds were characterized by spectroscopic techniques such as EIMS, 1 H-NMR and 13 C-NMR. Compound 1 showed signific...

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Bibliographic Details
Published inJournal of asian natural products research Vol. 23; no. 9; pp. 899 - 905
Main Authors Rabbi, Fazle, Zada, Amir, Adhikari, Achyut, Nisar, Amna, Khalil, Saifullah Khan
Format Journal Article
LanguageEnglish
Published England Taylor & Francis 02.09.2021
Taylor & Francis Ltd
Subjects
Acetic acid
Cell lines
Coumarin
Cytotoxicity
Ethyl acetate
Lethality
MESD
NMR
Nuclear magnetic resonance
spectroscopy
Sterculia diversifolia
Sterculiaceae
Toxicity
Sterculia diversifolia
spectroscopy
MESD
Sterculiaceae
coumarin
cytotoxicity
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Summary:One new coumarin (stercularin), along with eleven known compounds, was isolated for the first time from ethyl acetate fraction of Sterculia diversifolia. The structures of isolated compounds were characterized by spectroscopic techniques such as EIMS, 1 H-NMR and 13 C-NMR. Compound 1 showed significant cytotoxicity by brine shrimp lethality assay (LD 50 : 8.00 μg/ml) and PC-3 cell lines protocol (IC 50 : 3.92 ± 0.20 μg/ml), respectively.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
ISSN:1028-6020
1477-2213
DOI:10.1080/10286020.2020.1791099