Evaluation of autologous platelet-rich plasma plus ablative carbon dioxide fractional laser in the treatment of acne scars

• Published in: Journal of cosmetic and laser therapy Vol. 20; no. 2; pp. 106 - 113
• Main Authors: Abdel Aal, Ahmed Mohammed, Ibrahim, Ibrahim Maeraj, Sami, Nevein Ahmed, Abdel Kareem, Ibrahim Mohammed
• Format: Journal Article
• Language: English
• Published: England 01.04.2018
• Subjects: Acne Vulgaris - complications; Adolescent; Adult; Cicatrix - etiology; Cicatrix - radiotherapy; Egypt; Face; Female; Humans; Lasers, Gas - adverse effects; Lasers, Gas - therapeutic use; Low-Level Light Therapy - adverse effects; Low-Level Light Therapy - methods; Male; Patient Satisfaction; Platelet-Rich Plasma; Single-Blind Method; Young Adult; fractional CO2 laser; Acne scars; platelet-rich plasma (PRP)
• ISSN: 1476-4172; 1476-4180
• DOI: 10.1080/14764172.2017.1368667

Acne scar is a common distressing complication of acne vulgaris. CO laser resurfacing proved effective for the treatment of this problem, but the associated complications may limit its use. Platelet-rich plasma (PRP) may increase the chance of favorable outcome. To evaluate the synergistic effects of autologous PRP with fractional CO laser resurfacing in the treatment of acne scars among Egyptian patients. This study included 30 patients suffering from post-acne scars. CO laser treatment was applied to both sides of the face followed by PRP injection for the right side. Evaluation was carried out through operating physicians, two blinded physicians as well as through patient's satisfaction. The right side of the face (PRP-treated side) achieved excellent improvement in 13.3% of the patients, while there was no excellent improvement on the left side. Combination of fractional CO laser resurfacing and intradermal PRP was superior to CO laser alone for acne scar treatment.