Determination of the amorphicity and glass transition temperatures (Tg) of some natural polysaccharides

This paper describes the determination of the glass transition temperature and the amorphicity of some natural gums. These two parameters are very important in pharmaceutical material science. Standard instrumental procedures were used in the determination. Results obtained were used to further char...

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Bibliographic Details
Published inJournal of drug delivery science and technology Vol. 18; no. 3; pp. 219 - 220
Main Authors Attama, A.A., Akpa, P.A.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 2008
Subjects
Amorphicity
Application
Glass transition
Natural polysaccharides
Thermal properties
Thermal properties
Glass transition
Natural polysaccharides
Amorphicity
Application
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Summary:This paper describes the determination of the glass transition temperature and the amorphicity of some natural gums. These two parameters are very important in pharmaceutical material science. Standard instrumental procedures were used in the determination. Results obtained were used to further characterize these functional polysaccharides that have been investigated in the formulation of some dosage forms, without to date adequately describing their thermal and crystal properties. Knowledge of the thermal and crystal properties will widen the horizon of usage of these emerging functional pharmaceutical excipients.
ISSN:1773-2247
DOI:10.1016/S1773-2247(08)50040-2