An electrochemical DNA sensor based on an integrated and automated DNA walker

• Published in: Bioelectrochemistry (Amsterdam, Netherlands) Vol. 147; p. 108198
• Main Authors: Fan, Hao, Wu, Ying, Huang, Tongfu, Hong, Nian, Cui, Hanfeng, Wei, Guobing, Liao, Fusheng, Zhang, Jing
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.10.2022; Elsevier BV
• Subjects: Automated; Automation; Biosensors; Carboxylic acids; DNA walker; DNAzyme-driven; Electrochemistry; Electrodes; Integrated; Locking; MOFs; Nucleotide sequence; Single-stranded DNA; Strands; Zirconium; DNAzyme-driven; MOFs; Automated; Integrated; DNA walker

[Display omitted] •A DNA nanomachine is constructed by combining the DNA walker and Mn2+@MOFs.•Mn2+ was loaded into nano-MOFs containing free carboxyl groups UIO-66(Zr)-(COOH)2.•The detection limit of this biosensor was as low as 38 fM.•let-7a and C. sinensis DNA can be detected in real sample. As a...