Bacteria-based cancer therapy: Looking forward

The field of bacteria-based cancer therapy, which focuses on the key role played by the prevalence of bacteria, specifically in tumors, in controlling potential targets for cancer therapy, has grown enormously over the past few decades. In this review, we discuss, for the first time, the global canc...

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Published inBiochimica et biophysica acta. Reviews on cancer Vol. 1879; no. 4; p. 189112
Main Authors Tieu, My-Van, Pham, Duc-Trung, Cho, Sungbo
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.07.2024
Subjects
Animals
Bacteria - genetics
Bacteria cancer therapy
Biological engineering
Engineered bacteria
Humans
Neoplasms - therapy
Wild-typed bacteria
Engineered bacteria
Bacteria cancer therapy
Wild-typed bacteria
Biological engineering
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Summary:The field of bacteria-based cancer therapy, which focuses on the key role played by the prevalence of bacteria, specifically in tumors, in controlling potential targets for cancer therapy, has grown enormously over the past few decades. In this review, we discuss, for the first time, the global cancer situation and the timeline for using bacteria in cancer therapy. We also explore how interdisciplinary collaboration has contributed to the evolution of bacteria-based cancer therapies. Additionally, we address the challenges that need to be overcome for bacteria-based cancer therapy to be accepted in clinical trials and the latest advancements in the field. The groundbreaking technologies developed through bacteria-based cancer therapy have opened up new therapeutic strategies for a wide range of therapeutics in cancer.
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ISSN:0304-419X
1879-2561
1879-2561
DOI:10.1016/j.bbcan.2024.189112