Efficacy and safety of intense pulsed light in the treatment of inflammatory acne vulgaris with a novel filter

• Published in: Journal of cosmetic and laser therapy Vol. 21; no. 6; pp. 323 - 327
• Main Authors: Chen, Sunyi, Wang, Yan, Ren, Jie, Yue, Baishuang, Lai, Guanyin, Du, Juan
• Format: Journal Article
• Language: English
• Published: England 18.08.2019
• Subjects: Acne Vulgaris - therapy; Adolescent; Adult; Face - pathology; Female; Humans; Intense Pulsed Light Therapy - adverse effects; Intense Pulsed Light Therapy - methods; Male; Prospective Studies; Severity of Illness Index; Treatment Outcome; Young Adult; Acne vulgaris; intense pulsed light therapy
• ISSN: 1476-4172; 1476-4180; 1476-4180
• DOI: 10.1080/14764172.2019.1605450

Acne vulgaris is one of the most common skin diseases affecting young people. Intense pulsed light (IPL) has become a well-recognized method in the treatment of acne vulgaris. We aim evaluate the clinical efficacy and safety of a novel IPL filter at wavelength of 400-600 nm and 800-1,200 nm in the treatment of inflammatory acne lesions. Twenty-one patients with Pillsbury I-III facial acne vulgaris between July 2017 and January 2018 were enrolled in this prospective clinical study. Five sessions of IPL treatment were administered to the subjects at 4-week interval. Final assessment was performed 1 month after the final treatment. One month posttreatment, over 75% subjects exhibited excellent or good response. Of the Pillsbury I-II patients, the effective rate reached 88.24%. The inflammatory lesions were dramatically decreased (25.23 ± 2.76 versus 14.01 ± 1.98) and statistically evident ( = .031). According to Hayashi assessment of acne severity, there was a significant improvement at follow-up visit ( = .022). Moreover, patients reported significant improvements in self-evaluation. The novel IPL filter at wavelength of 400-600 nm and 800-1,200 nm provides an effective option to treatment of inflammatory acne lesions, especially for Pillsbury I-II acne patients, with minimal reversible side effects, such as transient post-inflammatory pigmentation.