Pediatric GIST presenting as anemia

Gastrointestinal stromal tumors (GIST) are tumors of the gastrointestinal (GI) tract originating from the myenteric ganglion cells (interstitial cells of Cajal), that are very rare in children and adolescents. The most common clinical manifestation is acute or chronic, overt or occult GI bleeding al...

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Published inPediatric hematology and oncology Vol. 34; no. 5; pp. 343 - 347
Main Authors Cianci, Paola, Luini, Chiara, Marinoni, Maddalena, Nespoli, Luigi, Salvatoni, Alessandro, Salvatore, Silvia
Format Journal Article
LanguageEnglish
Published England 01.08.2017
Subjects
Anemia, Iron-Deficiency - diagnosis
Child
Female
Gastrointestinal Hemorrhage - diagnosis
Gastrointestinal Neoplasms - diagnosis
Humans
GIST
gastrointestinal stromal tumor
fecal blood
Anemia
children
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Summary:Gastrointestinal stromal tumors (GIST) are tumors of the gastrointestinal (GI) tract originating from the myenteric ganglion cells (interstitial cells of Cajal), that are very rare in children and adolescents. The most common clinical manifestation is acute or chronic, overt or occult GI bleeding although these tumors are asymptomatic in 10-30% of patients. We report a case of gastric GIST in a 11-year-old girl presenting with an iron deficiency refractory anemia without gastrointestinal symptoms and stool evidence of GI bleeding that caused a slight diagnostic delay.
Bibliography:ObjectType-Case Study-2
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ISSN:0888-0018
1521-0669
DOI:10.1080/08880018.2017.1396387