Deafness associated with oral furosemide

A patient with Hodgkin's disease and renal insufficiency became deaf while being treated with high dose oral furosemide. Cessation of furosemide was associated with improvement in his hearing. However, at the time of his death, 11 days after stopping the furosemide, significant hearing impairme...

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Bibliographic Details
Published inSouthern medical journal (Birmingham, Ala.) Vol. 71; no. 1; p. 86
Main Authors Rifkin, S I, de Quesada, A M, Pickering, M J, Shires, Jr, D L
Format Journal Article
LanguageEnglish
Published United States 01.01.1978
Subjects
Aged
Audiometry
Deafness - chemically induced
Furosemide - adverse effects
Furosemide - therapeutic use
Hodgkin Disease - complications
Hodgkin Disease - drug therapy
Hodgkin Disease - radiotherapy
Humans
Male
Nephrotic Syndrome - complications
Nephrotic Syndrome - drug therapy
Prednisone - therapeutic use
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Summary:A patient with Hodgkin's disease and renal insufficiency became deaf while being treated with high dose oral furosemide. Cessation of furosemide was associated with improvement in his hearing. However, at the time of his death, 11 days after stopping the furosemide, significant hearing impairment was still present. It is suggested that oral furosemide be considered potentially ototoxic, particularly in patients with compromised renal function.
ISSN:0038-4348
DOI:10.1097/00007611-197801000-00029