Rhomboidal Pt(II) Metallacycle-Based Hybrid Viral Nanoparticles for Cell Imaging

Supramolecular coordination complexes (SCCs) have emerged as anticancer agents. Tracking the movement of these metallic anticancer agents plays an important role in the field of biomedicines. Herein, we describe a method for tracking the movement of a rhomboidal Pt(II) metallacycle agent using the q...

Full description

Saved in:
Bibliographic Details
Published inInorganic chemistry Vol. 60; no. 1; pp. 431 - 437
Main Authors Li, Run-Hao, Feng, Xia-Yi, Zhou, Juan, Yi, Fan, Zhou, Zhong-Qiang, Men, Dong, Sun, Yue
Format Journal Article
LanguageEnglish
Published United States 04.01.2021
Online AccessGet full text

Cover

More Information
Summary:Supramolecular coordination complexes (SCCs) have emerged as anticancer agents. Tracking the movement of these metallic anticancer agents plays an important role in the field of biomedicines. Herein, we describe a method for tracking the movement of a rhomboidal Pt(II) metallacycle agent using the quantum dots encapsidation self-assembly system of viral proteins. When incubated with living Vero cells, self-assembly of hybrid viral nanoparticles were employed for simultaneous cell imaging and visual transmission of the Pt(II) metallacycle agent. Considering these results, we believe that the multifunctional biomaterials consisting of a supramolecular coordination complex and quantum dots provide a new alternative for probing of the delivery of Pt(II) metallacycle drugs.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0020-1669
1520-510X
DOI:10.1021/acs.inorgchem.0c03095