Effect of 6-Azathymine, an analog of thymine, on the urinary excretion of uracil
The administration of 6-azathymine, an analog of thymine, to mice resulted in the excretion of large amounts of uracil in urine. 6-Azathymine and 5-bromo-6-azauracil, but not 6-azauracil, 5-ethyl-6-azauracil or 5- n-propyl-6-azauracil inhibited the degradation of uracil by a particle-free fraction o...
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Published in | Biochimica et biophysica acta Vol. 61; no. 1; pp. 81 - 85 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier B.V
09.07.1962
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Subjects | |
Online Access | Get full text |
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Summary: | The administration of 6-azathymine, an analog of thymine, to mice resulted in the excretion of large amounts of uracil in urine. 6-Azathymine and 5-bromo-6-azauracil, but not 6-azauracil, 5-ethyl-6-azauracil or 5-
n-propyl-6-azauracil inhibited the degradation of uracil by a particle-free fraction of rat liver. The enzymic degradation of uracil was inhibited by 6-azathymine to a greater extent then thymine. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0926-6550 0006-3002 1878-2256 |
DOI: | 10.1016/0926-6550(62)90033-6 |