Quantitative Concepts in Drug Formulation and Absorption and their Relevance for Drug Delivery

A series of theoretical models is presented to describe the processes of drug release and absorption following non-invasive administration by the intestinal and the (trans)dermal route. These models are used to analyze experimental data and provide the means to test hypotheses about the involved mec...

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Bibliographic Details
Published inChimia Vol. 60; no. 1-2
Main Authors Georgios Imanidis, Marc Sutter, Susanne Reitbauer, Susanne B. Kapitza, Peter van Hoogevest, Daniel Hummel, Beat Müller, Peter Lütolf
Format Journal Article
LanguageGerman
Published Swiss Chemical Society 01.01.2006
Subjects
(trans)dermal
Absorption
Drug delivery
Formulation
Intestinal
Modeling
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Summary:A series of theoretical models is presented to describe the processes of drug release and absorption following non-invasive administration by the intestinal and the (trans)dermal route. These models are used to analyze experimental data and provide the means to test hypotheses about the involved mechanisms and influence factors. They thus strengthen the basic understanding of drug release and absorption and help establish quantitative relationships that are relevant for the prediction and control of drug delivery.
ISSN:0009-4293
2673-2424
DOI:10.2533/000942906777675038